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line for layout purpose Detox Logo line for layout purpose line for layout purposeManagement of alcohol withdrawal: Quick reference guide line for layout purpose line for layout purpose
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How To Conduct Detoxification
 

How can I choose an appropriate level of care for my patient?

You can make a decision about appropriate level of care considering the following primary patient dimensions:

1. Acute intoxication and/or withdrawal potential, especially history of withdrawal     seizures
2. Biomedical conditions and complications
3. Emotional/behavioral conditions and complications including:

- Psychiatric conditions
- Psychological or emotional/behavioral complications of known or unknown origin
- Poor impulse control
- Change in mental status
- Transient neuropsychiatric complications

4. Treatment acceptance/resistance
5. Relapse/continued use potential
6. Recovery/living environment

Standardized assessments, such as the CIWA-Ar, may be used in addition to monitoring vital sign status and evidence of severe withdrawal by history. The patient's potential to complete detoxification should also be evaluated to determine the appropriate setting for stabilization

What are some detoxification protocols that I can use?

The follow PDF documents outline detoxification protocols for inpatient settings:

Alcohol Withdrawal Guidelines: Portland VA Medical Center
Alcohol Withdrawal Orders - VA Palo Alto Health Care System
Inpatient Alcohol Withdrawal Guidelines (VA Puget Sound)

Detoxification protocols for outpatient settings:

  • Medical or nursing staff should assess the patient in person, either daily or every other day (patient contact may be made by telephone on other days), to include:

    -
    Patient report of any alcohol use the previous day
    - Reported medication intake compared to the medication dispensed the previous day
    - Tremor, restlessness, and previous night's sleep
    - Observation of skin (e.g., color and turgor)
  • Urine toxicology or a breathalyzer test of BAC should be completed.
  • The patient should be medically cleared before initiating or continuing outpatient
    detoxification, if the daily screening is positive for any one of the following:

    - Blood sugar > 400 or positive anion gap
    - History of recent hematemesis or other GI bleeding disorder
    - Bilirubin > 3.0
    - Creatinine > 2.0
    - Systolic blood pressure > 180 or diastolic blood pressure > 110
    - Unstable angina
    - Temperature > 101 degrees
    - BAC > 0.08 on two outpatient visits

    What medications should I use for detoxification?
  • For the treatment of alcohol withdrawal, use benzodiazepines over non-benzodiazepine sedative-hypnotics because of documented efficacy, decreased abuse potential, and a greater margin of safety. Benzodiazepines are the drug of choice because they reduce withdrawal severity, incidence of delirium, and seizures. All benzodiazepines appear to be effective.

  • For geriatric patients, start with lower doses of benzodiazepines than for younger adults.

  • Shorter acting benzodiazepines that are metabolized by conjugation only (e.g. lorazepam) will have lower risk for acculation in populations possessing a significantly decreased capacity for metabolism by hepatic oxidation (e.g. end stage liver disease, elderly).

  • For managing alcohol withdrawal, carbamazepine can be used as an effective alternative to benzodiazepines.

  • Other agents, such as beta-blockers, dilantin, and clonidine, are generally not considered as appropriate monotherapy for alcohol withdrawal, but may be considered in conjunction with benzodiazepines in certain patients.


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Center for Health Care Evaluation
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